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FLASH GENE
Symbol FOXJ2 contributors: - updated : 09-03-2005
HGNC name forkhead box J2
HGNC id 24818
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a transactivation domain of the acidic type,onsly present in FHX-L
  • two tyrosine residues and a stretch of basic amino acid residues at the N and C-terminal ends of the fork head domain, important for its nuclear targeting
  • two other transactivation domains: domain I, at the N terminus, and the H/P domain, rich in histidine and proline residues
  • HOMOLOGY
    Homologene
    FAMILY forkhead family of transcriptional factors
    CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION transcriptional activator. able to bind to two different type of DNA binding sites
    CELLULAR PROCESS nucleotide, transcription
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS