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FLASH GENE

Symbol

SLC46A2

contributors: mct - updated : 16-07-2008

HGNC name	SLC46A2 solute carrier family 46, member 2
HGNC id	16055

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 4 - 2445 51.1 475 - Engelmark (2008)

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol blood / hematopoietic thymus       highly Urinary kidney       lowly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Lymphoid

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	twelve transmembrane region
	small segment of the central cytoplasmic loop

HOMOLOGY

Homologene

FAMILY	major facilitator superfamily
	SLC46A family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

having a role in both thymal development and the peripheral function of T-cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to cervical cancer with with high mean age at diagnosis

Variant & Polymorphism SNP	increasing the risk of cervical cancer with with high mean age at diagnosis

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS