Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol RBM12 contributors: mct - updated : 16-11-2006
HGNC name RNA binding motif protein 12
HGNC id 9898
Location 20q11.21      Physical location : 34.236.887 - 34.252.838
Synonym name
  • SH3/WW domain anchor protein in the nucleus
  • Synonym symbol(s) KIAA0765, SWAN, HRIHFB2091
    DNA
    TYPE functioning gene
    SPECIAL FEATURE overlapping, gene in gene
    text overlapping with CPNE1
    STRUCTURE 16.00 kb     4 Exon(s)    1 Copie(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Promoter
    Binding site
    text structure
  • RNA binding sites
  • promoter and 5 primeUTR sharing between CPNE1 and RBM12 )
  • MAPPING cloned Y linked N status confirmed
    Physical map
    TRPC4AP 20q11.23 transient receptor potential cation channel, subfamily C, member 4 associated protein C20orf31 20q11.23 chromosome 20 open reading frame 31 PROCR 20q11.21 protein C receptor, endothelial (EPCR) MMP24 20q11.2 matrix metalloproteinase 24 (membrane-inserted) ITGB4BP 20q11.2 integrin beta 4 binding protein C20orf128 20q11.21 chromosome 20 open reading frame 128 C20orf44 20q11.23 chromosome 20 open reading frame 44 GDF5 20q11.2 growth differentiation factor 5 (cartilage-derived morphogenetic protein-1) CEP2 20pter-q12 centrosomal protein 2 LOC343705 20q11.23 similar to beta-galactoside alpha-2,3-sialyltransferase C20orf173 20q11.22 chromosome 20 open reading frame 173 SDBCAG84 20pter-q12 serologically defined breast cancer antigen 84 FER1L4 20q11.21 fer-1-like 4 (C. elegans) RPL37P1 11q13 ribosomal protein L37 pseudogene 1 LOC375095 20q11.23 similar to dJ309K20.1.1 (novel protein similar to dysferlin, isoform 1) SPAG4 20q11.2 sperm associated antigen 4 CPNE1 20q11.21 copine I RBM12 20q11.21 RNA binding motif protein 12 NFS1 20q11-q12 NFS1 nitrogen fixation 1 (S. cerevisiae) C20orf52 20q11.23 chromosome 20 open reading frame 52 RNPC2 20q11.21 RNA-binding region (RNP1, RRM) containing 2 C20orf53 20 chromosome 20 open reading frame 53 C20orf104 20q11.22-q11.23 chromosome 20 open reading frame 104 SCAND1 20q11.1-q11.23 SCAN domain containing 1 C20orf152 20q11.23 chromosome 20 open reading frame 152 HMG4L2 20q11.23 high-mobility group (nonhistone chromosomal) protein 4-like 2 EPB41L1 20q11.2-q12 erythrocyte membrane protein band 4.1-like 1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - splicing 6640 97.3 932 - Huang (unpublished)
  • 3 exons
  • encoding the same protein than variant 2
  • - splicing 6608 97.3 932 - Huang (unpublished)
  • 3 exons
  • using a different splice site to create a shorter 5' UTR compared to variant 1
  • encoding the same protein than variant 1
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon moderately
     mouth   moderately
     stomach   moderately
    Endocrinethyroid   moderately
    Lymphoid/Immunethymus   moderately
     tonsils   predominantly
    Reproductivefemale systemuteruscervix moderately
     female systemovary  moderately
    Respiratoryrespiratory tracttrachea  highly
    Skin/Tegumentskin   moderately
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    Connectivebone  moderately
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion highly in lymph
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three RNA recognition motif (RRM) domains
  • two proline rich regions
  • two repetitive structural consensus motifs
  • five distinct RNA binding motifs
  • three putative transmembrane domains
  • a nuclear targeting sequence
  • a mitochondrial targeting sequence
  • conjugated PhosphoP
    HOMOLOGY
    interspecies homolog to rattus Rbm12 (84.9 pc)
    homolog to murine Rbm12 (86.5 pc)
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA binding
    small molecule
    protein interacting with CPNE1
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS