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FLASH GENE
Symbol CCL16 contributors: - updated : 01-04-2006
HGNC name chemokine (C-C motif) ligand 16
HGNC id 10614
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • four cysteines conserved among the CC family
  • HIF1 binding site
  • isoforms Precursor
    HOMOLOGY
    Homologene
    FAMILY intercrine beta family (small inducible cytokine, chemokine beta), CC subfamily
    CATEGORY signaling cytokine
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • lymphocyte and monocyte chemoattractant
  • showing a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells
  • CELLULAR PROCESS cell migration & motility
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other upregulated by IL-10.
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS