Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TXNRD1 | contributors: - updated : 14-06-2007 |
HGNC name | thioredoxin reductase 1 |
HGNC id | 12437 |
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Location | 12q23-q24 Physical location : 104.609.558 - 104.744.058 |
Synonym name | |
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Synonym symbol(s) | TXR,TR1,TXNR,TRXR1, TR, GRIM12 |
EC.number | 1.8.1.9 |
DNA |
TYPE | functioning gene |
STRUCTURE | 63.00 kb 16 Exon(s) |
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10 Kb 5' upstream gene genomic sequence study |
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regulatory sequence | Promoter |
cytosine-phosphate-guanine/HTF | |
Binding site | |
text structure | |
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MAPPING | cloned | Y | linked | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | homolog to chimpanzee TXNRD1 (99.60 pc) |
homolog to rattus Txnrd1 (90.78 pc) | |
homolog to murine Txnrd1 (91.58 pc) | |
homolog to chicken TXNRD1 (85.31 pc) |
Homologene |
FAMILY | pyridine nucleotide-disulfide oxidoreductase class-1 family |
CATEGORY | enzyme , signaling |
SUBCELLULAR LOCALIZATION
| intracellular |
intracellular,cytoplasm |
basic FUNCTION | key enzyme in the regulation of the intracellular redox environment |