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FLASH GENE
Symbol NPTX1 contributors: mct - updated : 28-03-2022
HGNC name neuronal pentraxin I
HGNC id 7952
ASSOCIATED DISORDERS
corresponding disease(s) SCA50
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in colon cancer
constitutional       gain of function
is rapidly upregulated during neural induction from human pluripotent stem cells (hPSCs)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • acts as a prognostic indicator in gastric cancer
  • potential diagnostic and prognostic biomarker in lung cancer (PMID;
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestivecolon
    NPTX1 suppress the colon cancer cell growth and might serve as a useful potential target for treatment of colon cancer
    ANIMAL & CELL MODELS