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FLASH GENE
Symbol ABCA5 contributors: - updated : 29-03-2006
HGNC name ATP-binding cassette, sub-family A (ABC1), member 5
HGNC id 35
Location 17q24.2-q24.3      Physical location : 67.240.575 - 67.323.323
Synonym symbol(s) ABC4, ABC13, KIAA1888, FLJ16381
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text clustered among 4 other ABC1 family members on 17q24
STRUCTURE 68.00 kb     38 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
CACNG5 17q24 calcium channel, voltage-dependent, gamma subunit 5 CACNG4 17q24 calcium channel, voltage-dependent, gamma subunit 4 CACNG1 17q24 calcium channel, voltage-dependent, gamma subunit 1 HELZ 17q24.2 helicase with zinc finger domain PSMD12 17q24.3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 PITPNC1 17q24.3 phosphatidylinositol transfer protein, cytoplasmic 1 DKFZP586L0724 17q24.3 DKFZP586L0724 protein LOC253924 17q24.3 similar to 60S ribosomal protein L17 (L23) FALZ 17q24 fetal Alzheimer antigen LOC284018 17q24.3 hypothetical protein LOC284018 LOC390809 17 similar to KIAA0563 protein LOC388413 17 similar to PP905 LOC51321 17q24.3 hypothetical protein LOC51321 SLC16A6 17q25.1 solute carrier family 16 (monocarboxylic acid transporters), member 6 KIAA1001 17q23-q24 solute carrier family 16 (monocarboxylic acid transporters), member 6 FLJ10055 17q24.3 hypothetical protein FLJ10055 PRKAR1A 17q23-q24 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) FAM20A 17q24.3 family with sequence similarity 20, member A ABCA8 17q24 ATP-binding cassette, sub-family A (ABC1), member 8 ABCA9 17q24 ATP-binding cassette, sub-family A (ABC1), member 9 ABCA6 17q24.2 ATP-binding cassette, sub-family A (ABC1), member 6 ABCA10 17q24 ATP-binding cassette, sub-family A (ABC1), member 10 ABCA5 17q21-q25 ATP-binding cassette, sub-family A (ABC1), member 5 MAP2K6 17q23.1-q24.2 mitogen-activated protein kinase kinase 6 LOC388414 17 LOC388414 LOC388415 17 LOC388415 KCNJ16 17q23.1-q21.2 potassium inwardly-rectifying channel, subfamily J, member 16 KCNJ2 17q23.1-q24.2 potassium inwardly-rectifying channel, subfamily J, member 2 LOC390810 17 similar to calmodulin - rabbit (tentative sequence) LOC124685 17q25.1 similar to smooth muscle and non-muscle myosin alkali light chain isoform 1
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 7044 - 1642 - Petry
- - 5939 - 1642 - Petry
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrineparathyroid   highly
Reproductivemale systemtestis   
Respiratoryrespiratory tractlarynx  highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two ATP binding and two transmembrane (2TM) domains (2 x 6 segments)
  • two ABC transporter domains
  • HOMOLOGY
    interspecies homolog to murine Abc4
    Homologene
    FAMILY ATP binding cassette superfamily
    CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION having an ATPase activity
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS