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FLASH GENE

Symbol

MYO1D

contributors: - updated : 28-03-2006

HGNC name	myosin ID
HGNC id	7598

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19p13.3-p13.2      Physical location : 30.819.627 - 31.203.902
Synonym symbol(s)	KIAA0727, myr4

DNA

TYPE	functioning gene
STRUCTURE	384.00 kb     22 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon   highly   mouth tongue     highly Hearing/Equilibrium ear inner cochlea     Nervous brain       highly Reproductive female system ovary     highly Respiratory respiratory tract larynx     highly   respiratory tract trachea     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	N terminal motor domain with ATP and actin-binding sites
	a neck containing two IQ calmodulin or calmodulin-like light chain binding domains
	a tail with two TH and one SH3 motifs
	a myosin head-like domain
	a C terminal globular domain

HOMOLOGY

interspecies

homolog to murine Myo1f

Homologene

FAMILY

myosin family

CATEGORY

motor/contractile

SUBCELLULAR LOCALIZATION

basic FUNCTION	unconventional, apparently non filamentous, actin-based motor molecules with ATPase activity
	playing a role in intracellular movements

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

sensory transduction/hearing

a component

INTERACTION

DNA

RNA

small molecule

protein

binds calmodulin through its IQ motifs

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS