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FLASH GENE
Symbol RDH5 contributors: - updated : 24-03-2007
HGNC name retinol dehydrogenase 5 (11-cis and 9-cis)
HGNC id 9940
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • two transmembrane segments (TM2)
  • the catalytic domain on the lumenal compartment
    • HOMOLOGY
    interspecies ortholog to murine Rdh5
    Homologene
    FAMILY short chain alcohol dehydrogenase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION final step in the synthesis of 11-cis retinaldehyde
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling sensory transduction/vision
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) RDH5
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS