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FLASH GENE
Symbol RHD contributors: mct - updated : 15-11-2011
HGNC name Rhesus blood group, D antigen
HGNC id 10009
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • twelve transmembrane segments (12TM)
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY antigen , transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in ammonium transport
  • RHCE and RHD, may not function directly in ammonia transport and may be evolving a new function in the red blood cell membrane
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of a complex with RHCE
  • fatty acylated integral red cell membrane protein component
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other cell surface expression posttranscriptionally regulated by RHAG
    ASSOCIATED DISORDERS
    corresponding disease(s) RH , RHECT
    Susceptibility
    Variant & Polymorphism other totally or partially absent in the Caucasian RH-negative phenotype
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS