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FLASH GENE
Symbol RHD contributors: mct - updated : 15-11-2011
HGNC name Rhesus blood group, D antigen
HGNC id 10009
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinelarge intestinecolon  
 stomach    
Urinarybladder    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticerthrocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES Hydrophobic
STRUCTURE
motifs/domains
  • twelve transmembrane segments (12TM)
    • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY antigen , transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in ammonium transport
  • RHCE and RHD, may not function directly in ammonia transport and may be evolving a new function in the red blood cell membrane
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • component of a complex with RHCE
  • fatty acylated integral red cell membrane protein component
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other cell surface expression posttranscriptionally regulated by RHAG
    ASSOCIATED DISORDERS
    corresponding disease(s) RH , RHECT
    Susceptibility
    Variant & Polymorphism other totally or partially absent in the Caucasian RH-negative phenotype
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS