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FLASH GENE
Symbol RTN2 contributors: mct - updated : 14-04-2008
HGNC name reticulon 2
HGNC id 10468
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal luminal, negatively charged domain
  • two hydrophobic transmembrane segments (TH2)
  • a conserved C terminal region
    • HOMOLOGY
    Homologene
    FAMILY reticulon family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    text anchored to membranes of the endoplasmic reticulum through its carboxy-terminal regions
    basic FUNCTION
  • involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS