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FLASH GENE
Symbol RTN2 contributors: mct - updated : 14-04-2008
HGNC name reticulon 2
HGNC id 10468
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain   highly
Respiratoryrespiratory tractlarynx  highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a N terminal luminal, negatively charged domain
  • two hydrophobic transmembrane segments (TH2)
  • a conserved C terminal region
    • HOMOLOGY
    Homologene
    FAMILY reticulon family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    text anchored to membranes of the endoplasmic reticulum through its carboxy-terminal regions
    basic FUNCTION
  • involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS