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FLASH GENE
Symbol NARS1 contributors: mct - updated : 16-09-2020
HGNC name asparaginyl-tRNA synthetase
HGNC id 7643
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases
HOMOLOGY
Homologene
FAMILY class II family of tRNA synthetases
CATEGORY enzyme
SUBCELLULAR LOCALIZATION extracellular
    intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • involved in autoimmune reactions
  • is required to meet protein synthetic needs and to support radial glial cells (RGCs) proliferation in brain development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) MNDDSA
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS