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FLASH GENE
Symbol MYH7 contributors: mct/npt - updated : 16-01-2018
HGNC name myosin, heavy chain 7, cardiac muscle, beta
HGNC id 7577
ASSOCIATED DISORDERS
corresponding disease(s) CMD1S , MPD1 , MMS , SPMM
related resource FHC Mutation Database
Susceptibility to idiopathic dilated cardiomyopathy
Variant & Polymorphism other mutated in idiopathic dilated cardiomyopathy (Moller 2009)
Candidate gene
Marker
  • MYH7, IGFBP7, ANXA2, and DES are all excellent candidate plasma biomarkers of heart failure
  • Therapy target
    SystemTypeDisorderPubmed
    cardiovascularaquiredheart failure
    activation of myosin by omecamtiv mecarbil may provide a new therapeutic approach for systolic heart failure
    ANIMAL & CELL MODELS