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FLASH GENE

Symbol

RAB8A

contributors: mct/npt/pgu - updated : 05-02-2020

HGNC name	RAB8A, member RAS oncogene family
HGNC id	7007

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   reduced in intestinal epithelial cells of the microvillus inclusion disease patient constitutional   deletion     muscle-specific RAB8A deletion caused hyperlipidemia and exacerbated hepatosteatosis induced by a high-fat diet

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	RAB8A might be a new biomarker for endometrial cancer
Therapy target

ANIMAL & CELL MODELS