| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| constitutional
|
|
| --over
|
|
|
in type 2 diabetes |
| tumoral
|
|
| --low
|
|
silencing by methylation in esophageal squamous cell carcinoma  |
| constitutional
|
|
| --low
|
|
|
maternal and umbilical cord serum RBP4 levels were lower in patients with preeclampsia than in normal pregnant women in the third trimester of pregnancy |
| constitutional
|
|
| --low
|
|
|
in familial partial lipodystrophy |
| tumoral
|
|
| --over
|
|
|
in ovarian cancer cells promoting cancer cell migration and proliferation |
| constitutional
|
|
| --over
|
|
|
in insulin resistance and contributes to increased diabetes risk |
| constitutional
|
|
| --over
|
|
|
in liver, subcutaneous adipose tissue (SAT), and visceral adipose tissue (VAT) in morbidly obese subjects |
