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FLASH GENE
Symbol PZP contributors: - updated : 04-03-2006
HGNC name pregnancy-zone protein
HGNC id 9750
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases
    • mono polymer homomer , tetramer
    HOMOLOGY
    interspecies ortholog to chimpanzee pzp
    intraspecies homolog to A2M
    Homologene
    FAMILY protease inhibitor i39 (alpha-2- macroglobulin) family
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • inhibiting all four classes of proteinases by a unique trapping mechanism
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS