Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

PTHLH

contributors: mct/npt/pgu - updated : 21-10-2013

HGNC name	parathyroid hormone-like hormone
HGNC id	9607

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ECDMM2 , BDE2

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in prostate cancer cells

Susceptibility

Variant & Polymorphism

Candidate gene	occurrence of PTHLH may be an indication of developing oral malignant carcinomas
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive prostate targeting PTHLH in prostate cancer, thereby reversing the effect on caspase activity and alpha6beta4 levels, may thus prove therapeutically beneficial cancer bone   PTHLH neutralizing immunotherapy is an intriguing potential therapeutic strategy for Giant Cell Tumor of Bone.

ANIMAL & CELL MODELS