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FLASH GENE

Symbol

WARS

contributors: - updated : 22-02-2006

HGNC name	tryptophanyl-tRNA synthetase
HGNC id	12729

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	41.00 kb     11 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

Y

status

confirmed

Map	cen - SERPINA1 - D14S45 - D14S51 - D14S18 - D14S13 - WARS - D14S27 - D14S17 - D14S1 - D14S20 - D14S23 - IGHJ@ - qter
Authors	Börglum (96)

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed V1 - - 2884 - 471 - Bruneel V2 - - 2660 - 471 - Bruneel V3 - - 2488 - 430 - Bruneel V4 - - 2712 - 430 - Bruneel

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune spleen       highly Reproductive female system uterus cervix   highly   female system placenta     highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria

basic FUNCTION

catalyzing the aminoacylation of tRNA(trp) with tryptophan

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

induced by	interferon
		interferon

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS