Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
| germinal mutation
|
|
|
|
in pheochromocytoma and paraganglioma | tumoral
|
|
|
| loss of function
|
in pheochromocytoma and paraganglioma | tumoral
|
| LOH
|
|
|
in pheochromocytoma with high-risk of recurrence or malignancy | tumoral
| germinal mutation
|
|
|
|
in Cowden and Cowden-like syndromes | tumoral
| germinal mutation
|
|
|
|
in familial renal cell carcinoma, with early onset | tumoral
|
|
| --low
|
|
is limited to a distinctive subset of gastric wild-type gastrointestinal stromal tumours  | |