Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

ANG

contributors: mct/shn - updated : 08-09-2011

HGNC name	angiogenin, ribonuclease, RNase A family, 5
HGNC id	483

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ALS9

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in chronic heart failure (positively associated with age, plasma glucose, insulin, and BNP and negatively correlated with diastolic blood pressure and left ventricular ejection fraction) (Patel 2008)

Susceptibility

to amyotrophic lateral sclerosis

Variant & Polymorphism other	mutation loss of function in ALS

Candidate gene	for ALS
Marker
Therapy target	protects against dopaminergic neuronal cell death and suggests its potential as a therapy for Parkinson's disease (

ANIMAL & CELL MODELS

angiogenin-1 protein is dramatically reduced in this transgenic alpha-synuclein mouse model of Parkinson's disease (