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FLASH GENE
Symbol EVI2B contributors: SGE/npt - updated : 09-03-2010
HGNC name ecotropic viral integration site 2B
HGNC id 3500
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunethymus    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
 fibroblast
cell lineage
cell lines
fluid/secretion blood
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N-terminal signal peptide
  • an extracellular domain
  • four potential glycosylation sites
  • a single hydrophobic transmembrane domain
  • a cytoplasmic hydrophilic domain
    • conjugated GlycoP , PhosphoP
    isoforms Precursor
    HOMOLOGY
    interspecies ortholog to murine Evi2b
    Homologene
    FAMILY
    CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • involved in melanocyte and keratinocyte differentiation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS