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FLASH GENE

Symbol

CHRM1

contributors: mct - updated : 16-11-2015

HGNC name	cholinergic receptor, muscarinic 1
HGNC id	1950

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in schizophrenia tumoral   deletion     in neuroblastoma

Susceptibility

to numerous inflammatory diseases, including sepsis, Crohn disease and pancreatitis

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Chrm1 and Chrm3 double knockout chronically diminishes REM sleep to an almost undetectable level