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FLASH GENE
Symbol PPY contributors: - updated : 16-02-2006
HGNC name pancreatic polypeptide
HGNC id 9327
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a signal peptide
  • a pancreatic polypeptide sequence separated from the pancreatic icosapeptide sequence by a cleavage site, followed by a C terminal tyrosinamide
    • isoforms Precursor 95 aa polypeptide precursor cleaved into two peptide products; the active hormone of 36 aa and an icosapeptide of unknown function
    HOMOLOGY
    Homologene
    FAMILY NPY family
    CATEGORY signaling hormone
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • regulator of pancreatic and gastrointestinal functions
  • may be important in the regulation of food intake
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS