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FLASH GENE
Symbol ACP2 contributors: - updated : 12-10-2006
HGNC name acid phosphatase 2, lysosomal
HGNC id 123
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
Lymphoid/Immunespleen    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
histidine acid phosphatase domain
conjugated GlycoP
isoforms Precursor
HOMOLOGY
interspecies ortholog to murine Acp2
ortholog to rattus acp2
Homologene
FAMILY histidine acid phosphatase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,lysosome
basic FUNCTION
  • hydrolyzing orthophosphoric monoesters to alcohol and phosphate
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ACP2
    Susceptibility to progressive supranuclear palsy (PSP)
    Variant & Polymorphism SNP increasing the risk of progressive supranuclear palsy (PSP)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS