Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Orphanet Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol ACADS contributors: mct/npt - updated : 13-04-2018
HGNC name acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain
HGNC id 90
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , tetramer
HOMOLOGY
interspecies ortholog to rattus Acads
ortholog to murine Acads
Homologene
FAMILY
  • acyl-CoA dehydrogenase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,matrix
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • catalyzing the initial step of the mitochondrial fatty acid beta-oxidation pathway
  • transferring an electron to ETF
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism energetic , lipid/lipoprotein
    signaling
  • fatty acid beta oxidation
    • a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
  • FAD+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ACADS
    related resource MITOP database
    Susceptibility ethylmalonic aciduria
    Variant & Polymorphism with a frequent variant alleles 511C-511C>T, 625G>A, T625G-a conferring together susceptibility to ethylmalonic aciduria
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS