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FLASH GENE
Symbol A2M contributors: - updated : 29-09-2006
HGNC name alpha-2-macroglobulin
HGNC id 7
ASSOCIATED DISORDERS
corresponding disease(s) A2M
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral       loss of function
in clear cell renal carcinomas with poor outcome
Susceptibility to Alzheimer disease (AD5)
Variant & Polymorphism other
  • polymorphisms significantly associated with Alzheimer disease
  • A2M gene deletion associated with overweight and obesity in Thais
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS