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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CCL4

contributors: mct - updated : 06-05-2020

HGNC name	chemokine (C-C motif) ligand 4
HGNC id	10630

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in CD8+ cells and CD4+ cells in sarcoidosis

Susceptibility

to AIDS

Variant & Polymorphism SNP	influencing HIV Type 1 transmission and AIDS disease progression (Omim: 609423)

Candidate gene
Marker	variations in the CCL4 gene may help to predict breast cancer progression and metastasis
	decreased preclinical CCL3 and CCL4 levels might be associated with a subsequently increased risk of nasopharyngeal carcinoma
	CCL4 rs10491121 may be a factor to predict the tumor size in oral squamous cell carcinoma (OSCC) patients
Therapy target

ANIMAL & CELL MODELS