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FLASH GENE
Symbol CDK10 contributors: mct - updated : 17-10-2017
HGNC name cyclin-dependent kinase (CDC2-like) 10
HGNC id 1770
ASSOCIATED DISORDERS
corresponding disease(s) ALKAS
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in breast cancers and correlates with disease progression and poor survival
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • may serve as a prognostic biomarker for breast cancer
  • Therapy target
    SystemTypeDisorderPubmed
    cancerdigestiveliver
    potential therapeutic target for biliary tract cancer cells
    ANIMAL & CELL MODELS
  • homozygous Cdk10-knockout mice died postnatally with severe growth retardation, skeletal defects, and kidney and lung abnormalities