| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
|
| --over
|
| |
with CCND3 in agressive B cell lymphoma | | tumoral
|
|
| --low
|
| |
in the development and progression of oral squamous cell carcinoma and in thyroid, colon, breast, prostate and superficial bladder carcinoma | | tumoral
|
| deletion
|
|
| |
deleted in leukemia and other cancers with poor prognosis (pancreas adenocarcinoma, esophageal squamous cell carcinoma), degraded by proteasomes in gliomas | | tumoral
|
|
| --low
|
| |
(when inhibited by AKT1) in aggressive breast cancer | | tumoral
| germinal mutation
|
|
|
| |
in multiple endocrine neoplasia syndrome | | constitutional
|
|
| --low
|
| |
in both acute and end-stage heart failure | |
