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FLASH GENE
Symbol CDK3 contributors: - updated : 18-01-2006
HGNC name cyclin-dependent kinase 3
HGNC id 1772
Location 17q25      Physical location : 73.996.986 - 74.002.081
EC.number 2.7.1.-
DNA
TYPE functioning gene
STRUCTURE 4.00 kb     7 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuteruscervix highly
Skin/Tegumentskin   highly
Urinarybladder   highly
cell lineage
cell lines
fluid/secretion
at STAGE
cell cycle     cell cycle, checkpoint, G1S
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a PSTAIRE motif
HOMOLOGY
Homologene
FAMILY serine/threonine kinase, CDK subfamily
CATEGORY enzyme , regulatory
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
basic FUNCTION
  • involved in cell cycle regulation (G1 to S transition)
  • having a function in G1 progression that is different from cyclin D- or E-associated kinase activities
  • CELLULAR PROCESS cell life, proliferation/growth
    PHYSIOLOGICAL PROCESS
    text negative control
    PATHWAY
    metabolism
    signaling
    a component not complexing with any cyclin
    INTERACTION
    DNA
    RNA
    small molecule
    protein an unknown type of cyclin
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS