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FLASH GENE
Symbol RNH1 contributors: - updated : 13-12-2006
HGNC name ribonuclease/angiogenin inhibitor 1
HGNC id 10074
PROTEIN
PHYSICAL PROPERTIES acid
STRUCTURE
motifs/domains
  • fifteen LRR (leucine-rich) repeats
    • HOMOLOGY
    interspecies ortholog to murine Rnh1
    ortholog to rattus Rnh1
    ortholog to chimpanzee rnh
    Homologene
    FAMILY
  • family of proteinaceous cytoplasmic RNase inhibitors
    • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • acting as an inhibitor of pancreatic RNase and angiogenin
  • may also function in the modulation of cellular activities
  • may be essential for control of mRNA turnover
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism nucleic
    signaling
  • RNA catabolism
    • a component
  • forming a tight one-to-one complex with the RNase
    • INTERACTION
    DNA
    RNA binding
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS