| basic FUNCTION
| replacement histone protein, independent from the cell cycle |
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playing a role in the compaction of DNA into nucleosomes |
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H3F3A, H3F3B has multiple functions in distinct genomic locations that are not always correlated with an “active” chromatin state  |
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H3F3A, H3F3B are not required for active transcription but instead may be necessary for establishing a chromatin landscape allowing for proper gene expression upon differentiation |
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H3F3A, H3F3B are a crucial maternal factor for oocyte reprogramming, providing a practical model to directly dissect the oocyte for its reprogramming capacity |
