Symbol
| FGF8
| contributors: mct - updated : 12-12-2018
|
HGNC name
| fibroblast growth factor 8 (androgen-induced)
|
HGNC id
| 3686
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
tumoral
|  
|  
|  
| gain of function
|
in breast and eophageal cancers | tumoral
|  
|  
| --over
|  
|
in prostate cancer | tumoral
|  
|  
| --over
|  
|
in bone metastases of human prostate cancer | constitutional
| germinal mutation
|  
|  
|  
|
contribute to the formation of the VATER/VACTERL association | |
Susceptibility
|
to hypospadias |
Variant & Polymorphism
other
| polymorphisms increasing the risk of hypospadias |
|
|
Candidate gene
Marker
Therapy target
| | | |
| right isomerism in mutant mice -/- |