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FLASH GENE
Symbol FGF8 contributors: mct - updated : 12-12-2018
HGNC name fibroblast growth factor 8 (androgen-induced)
HGNC id 3686
ASSOCIATED DISORDERS
corresponding disease(s) KAL6 , BFPH
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral       gain of function
in breast and eophageal cancers
tumoral     --over  
in prostate cancer
tumoral     --over  
in bone metastases of human prostate cancer
constitutional germinal mutation      
contribute to the formation of the VATER/VACTERL association
Susceptibility to hypospadias
Variant & Polymorphism other polymorphisms increasing the risk of hypospadias
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
right isomerism in mutant mice -/-