basic FUNCTION
| calcium sensor for transmitter release at the central synapse, involved in exocytosis and endocytosis |
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functioning as a Ca2+ sensor for fast neurotransmitter release in caudal brain regions |
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major isoform of the synaptotagmin family at mammalian neuromuscular junctions (NMJs), functioning as a calcium sensor for neurotransmission |
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being an essential synaptotagmin isoform that functions in concert with other synaptotagmins in the Ca2+ triggering of neurotransmitter release |
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unlike neurons, the lack of SYT2 in mast cells was not associated with increased spontaneous exocytosis |
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controls regulated exocytosis but not other secretory responses of mast cells |
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negative regulator of chemotaxis |
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increases the dynamic range of synapses by driving release with a high CaČ+ cooperativity, as well as by suppressing a remaining, near-linear CaČ+ sensor |
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synaptic vesicle protein, major isoform of the synaptotagmin family at mammalian neuromuscular junctions (NMJs) and functioning as a calcium sensor for neurotransmission |
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regulates neurotransmitter release at human peripheral motor nerve terminals |
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SYT1 and SYT2 can redundantly control transmitter release at specific brain synapses |