| basic FUNCTION
| inhibitor of prostate tumor progression, preventing the local invasiveness  |
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inhibiting tumor growth and tumor angiogenesis, reducing osteolysis |
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playing an important role in the premalignancy of the prostate gland |
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may contribute to bladder cancer development and DNA methylation and histone deacetylation may be important for regulating maspin gene activation in bladder cancer cells |
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having a potential role for tumour metastasis in gastric cancer |
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modulating cell death and invasion in cervical cancer cells |
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might function with the cornea to regulate cell adhesion to extracellular matrix |
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blocking the growth, invasion and metastatic properties of mammary tumors |
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tumor inhibitor properties may be linked to its nuclear localization |
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suppressing the invasive ability of pancreatic ductal adenocarcinoma cells |
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plays a role in reducing the prostate tumor cell's ability to seed to bone |
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stimulates apoptosis, inhibits motility, invasion and cancer metastasis |
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may be restricted to an intracellular, possibly nuclear, role in which it influences cell-matrix interactions indirectly and is probably released only as a consequence of cell damage or necrosis |
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potentially exerts its role in the nucleus at the level of gene or chromatin regulation and thus indirectly affects the cell-matrix interaction or differentiation state |
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potent angiogenesis inhibitor and one of the key molecules that play a key role in endothelial cell (EC) cell adhesion and migration |
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affects cell adhesion and cytoskeleton reorganization through an integrin signal transduction pathway |
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decreases cell migration, invasion, proliferation, and angiogenesis, while increasing apoptosis and adhesion ( |
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