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	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

ITGA7

contributors: mct - updated : 21-03-2020

HGNC name	integrin, alpha 7
HGNC id	6143

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

ITGA7D

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in Acute myeloid leukemia (AML) with granulocytic sarcoma (GS)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	might serve as a potential biomarker for predicting increased AML risk and worse prognosis in AML patients
	is a glioblastoma biomarker
	prognostic factor in human Malignant pleural mesothelioma (MPM)
Therapy target
	System Type Disorder Pubmed cancer brain glioma/neuroblstoma is a glioblastoma candidate therapeutic target (PMID: 28602620) cancer digestive oesophagus could be a potential therapeutic target in oesophageal squamous cell carcinoma treatment

ANIMAL & CELL MODELS

alpha7 integrin null mices embryos exhibit vascular smooth muscle cell defects that result in cerebral vascular hemorrhaging