basic FUNCTION
| cell surface adhesion receptor mediating cell-adhesion to extra cellular matrix or to other cells, through hetero dimerization and connecting to the cytoskeleton and various signaling molecules within cells |
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critical roles of ITGA7 and UTRN in maintaining myotendinous junction structure and enabling force transmission during muscle contraction |
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is an epigenetically regulated tumour suppressor gene |
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plays a key functional role in growth and invasiveness of glioblastoma stem-like cells (GSCs) |
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playing a role in mechanical stabilization of muscle cells |
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promotes cell proliferation, stemness but suppresses cell apoptosis in non-small-cell lung cancer (NSCLC) |
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role of ITGA7 and extracellular matrix interactions in Acute myeloid leukemia (AML) cell proliferation and extramedullary disease development |