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FLASH GENE
Symbol EMR1 contributors: - updated : 23-03-2007
HGNC name egf-like module containing, mucin-like, hormone receptor-like sequence 1
HGNC id 3336
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunespleen    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticleukocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • five EGF-like domains
  • a seven-span transmembrane segment (7tm_2)
  • a G-protein-coupled receptor proteolytic site domain (GPS)
    • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to dog EMR1 (74.79 pc)
    Homologene
    FAMILY
  • G-protein coupled receptor superfamily
  • LN-TM7 subfamily
    • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • coupling with Gs alpha protein
  • activating adenylate cyclase
  • could be involved in cell-cell interactions
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal , signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS