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FLASH GENE
Symbol HSD17B2 contributors: npt/ - updated : 14-01-2006
HGNC name hydroxysteroid (17-beta) dehydrogenase 2
HGNC id 5211
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • short chain alcohol dehydrogenase
    • HOMOLOGY
    Homologene
    FAMILY
  • short-chain dehydrogenases/reductases (sdr) family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION
  • 17-beta-hydroxysteroid dehydrogenase, type II, NAD dependent
  • catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone
  • playing an essential role in the formation of active intracellular sex steroids
  • may be involved in the biological inactivation of these sex steroids
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling hormonal
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS