| basic FUNCTION
| acting as a potent and selective chemotactic inflammatory protein for CD4+ T lymphocytes |
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may be a marker of agressive behavior in invasive breast cancer |
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might play a role in the progression of skin cancer |
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may have consequential immunobiological effects during the fetal development |
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playing a role in modulating the immune response which may be a factor in early breast tumor progression (Mandal 2007) |
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enhances survival mechanisms in breast cells through an interaction with c-jun activation domain binding protein 1 (COPS5) (West 2009) |
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may mediate some of inflammatory cytokines effects in breast cancer (West 2010) |
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psoriasin is likely produced by the structures of the ocular surface and is part of the innate immune system at the ocular surface and tear film  |
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an antimicrobial role seems likely for psoriasin in sperm |
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is a positive regulator of survival and invasion of prostate cancer cells |
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estrogen-induced S100A7 expression mediated by KDM1A may downregulate breast cancer cell proliferation, implying a potential tumor suppressor-like function for S100A7 |
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psoriasin plays a role in the differentiation of luminal mammary epithelial cells |
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S100A7 and koebnerisin (S100A14) are released by keratinocytes during physiological wound healing |
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Psoriasin and koebnerisin show antifibrotic effects and may lead to novel preventive and therapeutic strategies for fibroproliferative diseases |
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functional role for AGER/S100A7 signaling in linking inflammation to aggressive breast cancer development |
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contributes likely to the dysregulated differentiation process in the psoriasis epidermis |
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metal-chelating protein expressed by epithelial cells |
