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FLASH GENE
Symbol ZNF160 contributors: np/ - updated : 12-05-2006
HGNC name zinc finger protein 160
HGNC id 12948
Location 19q13.41      Physical location : 53.569.867 - 53.606.687
Synonym name
  • KRAB zinc finger protein KR18
  • zinc finger protein HZF5
  • Synonym symbol(s) F11, HZF5, FLJ00032, HKr18, HZF5, KIAA1611, KR18, DKFZp686B16128
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text member of a cluster on 19q13
    STRUCTURE 36.82 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    6 - 4219 - 818 - -
    7 - 4304 - 818 - -
    7 - 4336 - 818 - -
    EXPRESSION
    Type ubiquitous
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveliver    
    Lymphoid/Immunespleen   highly
     thymus   highly
    Urinarybladder   highly
     kidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Connectivebonesubchondral  
    Connectivecartilage   
    Muscularstriatum   
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Blood/Hematopoieticmonocyte
    cell lineage
    cell lines monoblast cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • zinc finger protein
  • C2H2 type, Krüppel-like
  • one KRABA and one KRABB domain at the N terminus
  • conjugated MetalloP
    HOMOLOGY
    Homologene
    FAMILY
  • krueppel C2H2-type zinc-finger protein family
  • CATEGORY regulatory , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in transcriptionnal regulation
  • regulator of blood cells development
  • playing a role in renal development and maybe involved in the repair of the kidney
  • CELLULAR PROCESS nucleotide, transcription, regulation
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS development
    text hematopoiesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS