| protein
| interacting with SOX9 in the differentiation of endocardial cushion cells |
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interacting with SP7 to control osteoblastic bone formation |
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direct transcriptional target of RCAN1 within the endocardium during a critical window of heart valve formation |
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interacting with ATP6V0D2 (NFATC1/ATP6V0D2 and dendritic cell-specific transmembrane protein signaling axis plays a key role in the osteoclast multinucleation process, which is essential for efficient bone resorption)  |
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OSCAR is an important costimulatory receptor for osteoclast differentiation through activation of NFATC1 |
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demethylation of H3K27me3 in the NFATC1 gene locus by KDM6B plays a critical role in TNFSF11-induced osteoclast differentiation |
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GPC6 is a novel NFATC1, NFATC2, NFATC3, NFATC4 target gene in breast cancer cells that promotes invasive migration through WNT5A signalling |
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both FOXP3 and SIVA1 function as negative regulators of IL2 gene expression in Treg cells, via suppression of NFATC1 by FOXP3 and of NFKB1 by both FOXP3 and SIVA1 |
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IL2 upregulates CD86 expression on human CD4(+) and CD8(+) T cells via a receptor-dependent mechanism that involves the NFATC1 and mammalian target of rapamycin pathways |
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AKT2 a negative regulator of NFATC1 activation through its ability to inhibit calcium mobilization from the ER |
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KDM8 is a post-translational co-repressor for NFATC1 that attenuates osteoclastogenesis |
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synthesis of FN1 is mediated by a transcriptional complex consisting of NFATC1, SP7 and FOS |
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upon TNFSF11 activation, HDAC7 suppresses NFATC1 and prevents CTNNB1 down-regulation, thereby blocking osteoclast differentiation |
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SERPINA12 likely downregulates osteoclastogenesis in part by inhibiting expression of the transcription factor NFATC1 |
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mediates RHOA-induced FN1 upregulation in glomerular podocytes |
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FAM102A plays a critical role in TNFRSF11A-induced osteoclast differentiation, and its role may be closely related to the induction of NFATC1 |
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autocrine/paracrine role for RARRES2 in regulating osteoclast differentiation of hematopoietic stem cell (HSC) through modulating intracellular calcium and NFATC1 expression/activation |
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NFATC1 sequestering the SMAD3 prevents the proteasome mediated degradation of SKIL and SKIL has a role on the regulation of MMP2, MMP9 activity |
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ASIC1-mediated calcium entry plays a critical role in osteoclastogenesis by regulating activation of the NFATC1 |
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ETS1 promotes the expression of IL2 by modulating the activity of NFATC1 |
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NFATC1-mediated transcription regulates UTRN expression and FHL1 which promotes muscle hypertrophy, is a transcriptional activator of NFATC1 |
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GRK5-mediated pathological cardiac hypertrophy involves the activation of NFATC1 because GRK5 causes enhancement of NFATC1-mediated hypertrophic gene transcription |
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BSG plays a critical role in the differentiation and function of osteoclasts by upregulating NFATC1 through the autoamplification of its expression in osteoclastogenesis |
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TNFSF11-induced LDHA, LDHB activation stimulates glycolytic and mitochondrial respiratory metabolism, facilitating mature osteoclast formation via osteoclast precursor fusion and NFATC1 signaling |
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IKBKE promotes NFATC1 phosphorylation and inhibits T cell responses, identifying IKBKE as a crucial negative regulator of T cell activation |
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DYRK1A is a positive kinase in regulation of NFATC1 |
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biphasic roles of MTOR in osteoclastogenesis, dosage-dependent effects of rapamycin on bone, and a calcineurin-MTOR-NFATC1 phosphorylation-regulatory signaling cascade |
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STAT3 could drive the transcription of NFATC1 by binding to its promoter |
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DYRK1A activates NFATC1 to increase glioblastoma migration |
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GAP43 attenuated podocyte injury by inhibiting calcineurin/NFATC1 signaling |
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likely ESR1 interacts with NFATC1 to repress WNT5B protein expression |
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activation of NFATC1 represses osteoblastogenesis by activating WNT5B expression |
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CELF2 may inhibit breast cancer cell invasion and angiogenesis by downregulating NFATC1 |
