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FLASH GENE
Symbol PTGFR contributors: - updated : 14-09-2005
HGNC name prostaglandin F receptor (FP)
HGNC id 9600
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemprostate   
Visualeyeanterior segmentiris  
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connective    
Epithelial    
Muscularsmooth   
Muscularsmouthciliary  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM)
HOMOLOGY
interspecies homolog to murine Ptgfr
Homologene
FAMILY G protein coupled receptor superfamily
CATEGORY signaling , receptor membrane G
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • potent luteolytic agent, may be involved in modulating intraocular pressure and smooth muscle contraction in uterus
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral   LOH    
    in breast cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS