Other morbid association(s)
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Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
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constitutional
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low copy number was associated with glomerulonephritis in the autoimmune disease systemic lupus erythematosus | constitutional
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| --low
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may be a common genomic mechanism in the development of SLE, Wegener's granulomatosis and microscopic polyangiitis | constitutional
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| deletion
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juxtaposes the 5prime-regulatory sequences of FCGR2C with the coding sequence of FCGR2B, creating a chimeric gene that provides an explanation for SLE risk associated with reduced FCGR3B gene copy number  | constitutional
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| deletion
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is a risk factor for systemic sclerosis  | |