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FLASH GENE
Symbol CD79A contributors: np - updated : 03-01-2006
HGNC name CD79a molecule, immunoglobulin-associated alpha
HGNC id 1698
Corresponding disease
AGM3 agammaglobulinemia
Location 19q13.2      Physical location : 42.381.189 - 42.385.438
Synonym name
  • CD79A antigen (immunoglobulin-associated alpha)
  • Ig alpha component,B cell Ag receptor
  • CD79a antigen
  • membrane-bound immunoglobulin-associated protein
  • surface IgM-associated protein
  • MB-1 membrane glycoprotein
  • B-cell antigen receptor complex-associated protein alpha chain
    • Synonym symbol(s) BCRA, IGA, C79A, MB-1
    DNA
    TYPE functioning gene
    STRUCTURE 4.25 kb     5 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1258 21.8 226 - -
    5 - 1144 17.6 188 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Lymphoid/Immunespleen    
     thymus    
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Lymphoid/ImmuneB cell
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an immunoglobulin-like C2-type domain
    • mono polymer heteromer , dimer
    HOMOLOGY
    interspecies homolog to murine mb-1(Ig-alpha/mb-1)
    Homologene
    FAMILY
    CATEGORY antigen , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION may be involved in signal transduction
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component (47kDa) of Ig alpha
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) AGM3
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS