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FLASH GENE

Symbol

ADCY6

contributors: mct - updated : 14-10-2014

HGNC name	adenylate cyclase 6
HGNC id	237

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LCCS8

Susceptibility

to greater vascular sensitivity to the beta-adrenergic agonist isoproterenol

Variant & Polymorphism other	ADCY6 polymorphisms may influence sickle cell disease severity through the mechanism of sickle red cell adhesion
	genetic variant ADCY6 S674 had significantly greater vascular sensitivity to the beta-adrenergic agonist isoproterenol

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS