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FLASH GENE

Symbol

PCTK3

contributors: - updated : 28-12-2005

HGNC name	PCTAIRE protein kinase 3
HGNC id	8751

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed PCTK3 V1 or Ib - - 3165 - 504 limited to several subcortical nuclei of the basal gangli and the spinal cord Herskovits an insert that adds 90 nucleotides to the third exon PCTK3 V2 or Ia - - 3075 - 474 throughout the brain and in the majority of tissues analyzed Herskovits PCTK3 V3 - - 3157 - 474 - Herskovits

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon     Nervous brain         Reproductive female system ovary     highly Urinary bladder       highly Visual eye

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	serine/threonine kinase
	the PCTAIRE motif

HOMOLOGY

interspecies

homolog to cdc2

Homologene

FAMILY

PCTAIRE subfamily of CDC2-related serine/threonine protein kinases

CATEGORY

enzyme , receptor membrane serine/threonine kinase

SUBCELLULAR LOCALIZATION	extracellular
	intracellular
	intracellular,nucleus

basic FUNCTION

may play a role in signal transduction cascades in terminally differentiated cells

CELLULAR PROCESS	cell cycle

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS