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FLASH GENE

Symbol

POLR2E

contributors: mct - updated : 27-10-2011

HGNC name	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
HGNC id	9192

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

RPB5 RNA polymerase subunit family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,nucleoplasm

basic FUNCTION

catalyzing the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

CELLULAR PROCESS

nucleotide, replication

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	binding C19orf2
	hepatitis B virus X protein (HBx), a protein known to be a causative agent in the formation of hepatocellular carcinoma interacts directly with POLR2E

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS